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An evaluation of the accuracy of emergency physician activation of the cardiac catheterization laboratory for patients with suspected ST-segment elevation myocardial infarction.
Extensive aortic dissection presenting as acute inferior myocardial infarction.
Infections and severe sepsis in solid-organ transplant patients admitted from a university-based ED.
The Right Dose: From Phase I to Clinical Practice.
Brain white matter microstructure alterations in adolescent rhesus monkeys exposed to early life stress: associations with high cortisol during infancy.
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Gupta, Mahesh P.
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Gupta, Mahesh P.
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Concept
Enzyme Activation
Academic Article
Poly(ADP-ribose) polymerase-1-dependent cardiac myocyte cell death during heart failure is mediated by NAD+ depletion and reduced Sir2alpha deacetylase activity.
Academic Article
The deacetylase SIRT1 promotes membrane localization and activation of Akt and PDK1 during tumorigenesis and cardiac hypertrophy.
Academic Article
Activation of SIRT1, a class III histone deacetylase, contributes to fructose feeding-mediated induction of the alpha-myosin heavy chain expression.
Academic Article
Honokiol blocks and reverses cardiac hypertrophy in mice by activating mitochondrial Sirt3.
Academic Article
Regulation of Akt signaling by sirtuins: its implication in cardiac hypertrophy and aging.
Academic Article
SIRT3 Blocks Aging-Associated Tissue Fibrosis in Mice by Deacetylating and Activating Glycogen Synthase Kinase 3ß.
Academic Article
SIRT3 is attenuated in systemic sclerosis skin and lungs, and its pharmacologic activation mitigates organ fibrosis.
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Enzyme Activation